We present a 65 year old female patient presented with acute onset of severe left sided abdominal pain associated with a tender intra-abdominal lump over the left flank. An abdominal ultrasonography revealed an ectopic spleen in left flank and a CE-CT scan of abdomen confirmed the wandering spleen with torsion of vascular pedicle at the hilum. She underwent splenectomy. Wandering spleen is an uncommon clinical entity. Review of literature was made on different clinical presentations, diagnostic evaluation, treatment options, and clinical outcomes of patients with wandering spleen and discussed in this case report.